Dibutyryl lecithin

Dibutyryl lecithin - Names and Identifiers

Name	1,2-DIBUTYRYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms	Dibutyryl lecithin Dibutanoyllecithin L-ALPHA-PHOSPHATIDYLCHOLINE, DIBUTYRYL 1,2-DIBUTYRYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIBUTYROYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DITETRANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-(1-oxobutoxy)-3,5,9-trioxa-4-phosphatridecan-1-aminium 4-oxide, inner salt
CAS	3355-26-8

Dibutyryl lecithin - Physico-chemical Properties

Molecular Formula	C16H32NO8P
Molar Mass	397.401
Flash Point	11℃
Appearance	Morphological solution
Storage Condition	−20°C

Dibutyryl lecithin - Risk and Safety

Risk Codes	R45 - May cause cancer R46 - May cause heritable genetic damage R11 - Highly Flammable R23/25 - Toxic by inhalation and if swallowed. R36/38 - Irritating to eyes and skin. R48/20/22 - R40 - Limited evidence of a carcinogenic effect R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R63 - Possible risk of harm to the unborn child
Safety Description	S53 - Avoid exposure - obtain special instructions before use. S7 - Keep container tightly closed. S16 - Keep away from sources of ignition. S23 - Do not breathe vapour. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	3

Dibutyryl lecithin - Introduction

1, (1,) is a compound, often referred to as DBPC. The following is a description of its nature, use, preparation and safety information:

Nature:
DBPC is a pale yellow or yellow liquid. It is soluble in alcohols and lipids at room temperature, slightly soluble in water. It has a molecular weight of about 451.5g/mol.

Use:
DBPC is mainly used in the field of biochemical research and medicine. It is widely used as a component of drug delivery systems, especially for targeted drug delivery and controlled drug release. In addition, DBPC can be used as an analytical tool for cell membrane model studies and cholinesterase activity.

Method:
There are many preparation methods for DBPC, one of which is commonly used by the synthesis of phosphoric anhydride. The specific step is to condense glycerol with sodium phthalocyanine and bromobutyric acid to obtain 2-bromobutyryl-sn-glycerol-3-fatty acid ester, it is then converted to 2-dibutyryl-sn-glycero-3-phosphate via different chemical reactions.

Safety Information:
Although DBPC is widely used in many studies, its toxicity and safety need to be studied and confirmed. When using DBPC, it is recommended to take appropriate laboratory operations and personal protective measures, and to follow relevant safe operating procedures. Special care should be taken to avoid skin and eye contact, and to avoid inhalation and ingestion. Seek medical assistance in case of accidental exposure or discomfort.

Last Update：2024-04-09 20:52:54